The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2020
Filed:
Sep. 12, 2018
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Natalie Dales, Arlington, MA (US);
Paul Gormisky, Brookline, MA (US);
John Ryan Kerrigan, Wakefield, MA (US);
Lei Shu, Lexington, MA (US);
Assignee:
NOVARTIS AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/14 (2006.01); C07D 249/10 (2006.01); C07D 401/10 (2006.01); C07D 401/14 (2006.01); C07D 487/04 (2006.01); C07D 405/10 (2006.01); C07D 403/10 (2006.01); A61P 27/16 (2006.01); A61P 21/00 (2006.01); A61P 25/28 (2006.01); A61P 17/02 (2006.01); C07D 413/10 (2006.01); C07D 405/14 (2006.01); C07D 417/10 (2006.01); C07D 491/04 (2006.01); C07D 333/20 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C07D 249/10 (2013.01); A61P 17/02 (2018.01); A61P 21/00 (2018.01); A61P 25/28 (2018.01); A61P 27/16 (2018.01); C07D 231/14 (2013.01); C07D 333/20 (2013.01); C07D 401/10 (2013.01); C07D 401/14 (2013.01); C07D 403/10 (2013.01); C07D 405/10 (2013.01); C07D 405/14 (2013.01); C07D 413/10 (2013.01); C07D 417/10 (2013.01); C07D 487/04 (2013.01); C07D 491/04 (2013.01); C07D 498/04 (2013.01);
Abstract
The present disclosure provides a compound of formula (I): or a pharmaceutically acceptable salt thereof, and its therapeutic uses for activating a growth factor pathway, promoting wound healing, promoting tissue repair, and treating hearing loss, skeletal muscle loss, organ degeneration, tissue damage, neurodegeneration, and muscular atrophy. The disclosure further provides pharmaceutical compositions and combinations. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.