The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2020

Filed:

Jan. 30, 2018
Applicant:

Curiox Biosystems Pte Ltd., Singapore, SG;

Inventors:

Namyong Kim, Allston, MA (US);

Siah Chong Cheong, Singapore, SG;

Hanwen Melvin Lye, Singapore, SG;

Mark Siew Peng Phong, Singapore, SG;

Li Li, Singapore, SG;

Teow Soon Seah, Singapore, SG;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); C12M 1/00 (2006.01); C12M 1/32 (2006.01);
U.S. Cl.
CPC ...
B01L 3/5085 (2013.01); B01L 3/50853 (2013.01); C12M 23/12 (2013.01); C12M 23/34 (2013.01); B01L 3/50855 (2013.01); B01L 2200/0689 (2013.01); B01L 2300/0618 (2013.01); B01L 2300/0829 (2013.01);
Abstract

An apparatus configured for improving retention of non-adherent cells is disclosed. The apparatus includes a plate that includes a number of elements having a first surface energy arranged in an array with an overlay, on the plate, having a second surface energy. The first surface energy results in a hydrophilic surface and the second surface energy results in a hydrophobic surface. A diameter of the elements is at least 1 mm. A height of the overlay having the second surface energy, which results in a hydrophobic surface, is between 5% and 100% of the diameter of the elements. The apparatus also includes a wall circumferential to the plate. A method for performing multiple reactions with the apparatus is also disclosed.


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