The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2020

Filed:

Dec. 31, 2015
Applicant:

Mount Sinai School of Medicine, New York, NY (US);

Inventors:

Daniel P Perl, Bethesda, MD (US);

Sharon Moalem, New York, NY (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61P 31/02 (2006.01); A61P 31/04 (2006.01); A61K 33/24 (2019.01); A23K 20/20 (2016.01); A61K 8/19 (2006.01); A61Q 11/00 (2006.01); A61Q 11/02 (2006.01); A61L 15/46 (2006.01); A23L 3/358 (2006.01); A61L 12/08 (2006.01); A61L 2/18 (2006.01); A61L 2/16 (2006.01); A61K 8/24 (2006.01); A61K 8/365 (2006.01); A23L 33/16 (2016.01); A01N 55/02 (2006.01); A01N 59/16 (2006.01); A61K 31/28 (2006.01);
U.S. Cl.
CPC ...
A61K 33/24 (2013.01); A01N 55/02 (2013.01); A01N 59/16 (2013.01); A23K 20/20 (2016.05); A23L 3/358 (2013.01); A23L 33/16 (2016.08); A61K 8/19 (2013.01); A61K 8/24 (2013.01); A61K 8/365 (2013.01); A61K 31/28 (2013.01); A61L 2/16 (2013.01); A61L 2/18 (2013.01); A61L 12/088 (2013.01); A61L 15/46 (2013.01); A61Q 11/00 (2013.01); A61Q 11/02 (2013.01); A23V 2002/00 (2013.01); A61K 2800/58 (2013.01); A61L 2300/102 (2013.01); A61L 2300/404 (2013.01); Y02A 50/473 (2018.01); Y02A 50/483 (2018.01);
Abstract

The present invention provides methods for treating or preventing diseases and disorders caused by iron-dependent pathogenic microorganisms, such as bacteria, fungi, and parasites, by applying a gallium compound to an affected area. In particular, the present invention provides methods for treating or preventing dental caries, vaginal infections, skin infections, and so forth. Gallium compounds can be formulated as toothpaste, mouthwash, cream, ointment, gel, solution, eye drops, suppository, and the like. Furthermore, the invention provides methods for controlling microbial growth on environmental surfaces, including those of toothbrush, denture, dental retainer, contact lens, catheter, food stuff, and so forth. In addition, the present invention provides animal feeds which contain gallium compounds that promote the animal growth and prevent the animals from infections as well as protect consumers from post processing infections.


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