The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2020
Filed:
Jul. 30, 2018
Applicant:
Autifony Theraputics Limited, Stevenage, Hertfordshire, GB;
Inventors:
Giuseppe Alvaro, Stevenage, GB;
Anne Decor, Verona, IT;
Stefano Fontana, Verona, IT;
Dieter Hamprecht, Verona, IT;
Charles Large, Stevenage, GB;
Agostino Marasco, Stevenage, GB;
Assignee:
AUTIFONY THERAPEUTICS LIMITED, Stevenage, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); C07D 233/76 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01); C07D 239/22 (2006.01); C07D 239/47 (2006.01); C07D 233/72 (2006.01); A61K 31/4166 (2006.01); A61K 31/4439 (2006.01); C07D 213/643 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61K 31/4166 (2013.01); A61K 31/4439 (2013.01); C07D 233/72 (2013.01); C07D 233/76 (2013.01); C07D 239/22 (2013.01); C07D 239/47 (2013.01); C07D 401/04 (2013.01); C07D 403/04 (2013.01); C07D 213/643 (2013.01);
Abstract
The invention provides a compound of formula (Ia), and pharmaceutically acceptable salts thereof. The invention also provides use of the compounds or salts as modulators of Kv3.1 and/or Kv3.2, and in the treatment of diseases or disorders where a modulator of Kv3.1 and/or Kv3.2 is required, such as depression and mood disorders, hearing disorders, schizopherenea, substance abuse disorders, sleep disorders or epilepsy.