The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2020
Filed:
Feb. 05, 2015
Kashiv Biosciences, Llc, Bridgewater, NJ (US);
Siva Ram Kiran Vaka, Piscataway, NJ (US);
Ashish Chatterji, East Brunswick, NJ (US);
Dipen Desai, Bridgewater, NJ (US);
Wantanee Phuapradit, Montville, NJ (US);
Navnit H. Shah, Clifton, NJ (US);
Atsawin Thongsukmak, Piscataway, NJ (US);
Kanji Meghpara, Morris Plains, NJ (US);
KASHIV BIOSCIENCES, LLC, Bridgewater, NJ (US);
Abstract
Disclosed are solid oral pharmaceutical compositions that that are intended to provide protection against overdose and tampering, as well as abuse deterrence. The compositions contain a plurality of granules or multi-particulates. A first population of multi particulates contains an API or drug susceptible to abuse, a polymer matrix, and an outer coating that contains a cationic pH dependent polymer. These multi particulates also contain a plasticizer and a surfactant. A second population of multi particulates contains a viscosity building polymer and an alkaline buffering agent. Compositions may further include a disintegrant, and/or additional viscosity building polymers and/or alkaline buffering agents and/or ion exchange polymers. Also disclosed are the methods of making and using the compositions.