The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2020

Filed:

Mar. 18, 2016
Applicant:

University of Connecticut, Farmington, CT (US);

Inventors:

Antonio Costa, Farmington, CT (US);

Diane J. Burgess, Farmington, CT (US);

Assignee:

University of Connecticut, Farmington, CT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); B01F 5/04 (2006.01); B01J 13/04 (2006.01); B01F 3/08 (2006.01); B01F 15/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1277 (2013.01); B01F 3/0807 (2013.01); B01F 5/045 (2013.01); B01F 15/00149 (2013.01); B01J 13/04 (2013.01); B01F 2215/0032 (2013.01);
Abstract

The present disclosure provides systems and methods for the continuous production of liposomes. An example method includes (a) mixing a solution of lipid and organic solvent from one or more containers to create an organic solvent-lipid solution, (b) providing the organic solvent-lipid solution to a first inlet of an injection port at a first flow rate, wherein the first inlet is in fluid communication with a first conduit, (c) providing an aqueous solution to a second inlet of the injection port at a second flow rate, wherein the second inlet is influid communication with a second conduit, wherein the first conduit is positioned concentrically within the second conduit at an outlet of the injection port, and wherein the first conduit extends through the outlet of the injection port, and (d) mixing the organic lipid solution and the aqueous solution to create a plurality of liposomes.


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