The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2020

Filed:

Mar. 04, 2016
Applicant:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

Inventors:

Samuel K. Sia, New York, NY (US);

Matthieu Jean Michel Rueegg, Saint-Sulpice, CH;

Nalin Tejavibulya, New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 5/1459 (2006.01); A61B 5/15 (2006.01); A61B 5/145 (2006.01); A61K 49/00 (2006.01); A61L 31/04 (2006.01); A61L 31/14 (2006.01); A61L 31/16 (2006.01); B29C 70/88 (2006.01); B29K 33/00 (2006.01); B29K 105/00 (2006.01); B29L 31/00 (2006.01);
U.S. Cl.
CPC ...
A61B 5/1459 (2013.01); A61B 5/0022 (2013.01); A61B 5/0071 (2013.01); A61B 5/145 (2013.01); A61B 5/14514 (2013.01); A61B 5/14532 (2013.01); A61B 5/14546 (2013.01); A61B 5/150022 (2013.01); A61B 5/150389 (2013.01); A61B 5/150984 (2013.01); A61B 5/685 (2013.01); A61K 49/0017 (2013.01); A61K 49/0073 (2013.01); A61L 31/048 (2013.01); A61L 31/145 (2013.01); A61L 31/16 (2013.01); B29C 70/88 (2013.01); A61B 2560/0214 (2013.01); A61B 2560/0242 (2013.01); A61B 2562/12 (2013.01); B29K 2033/26 (2013.01); B29K 2105/0061 (2013.01); B29K 2995/0035 (2013.01); B29L 2031/7544 (2013.01);
Abstract

At least one microneedle comprises a hydrogel material that includes a substance that fluoresces when the substance interacts with an analyte. A magnitude of the fluorescence varies as a function of the concentration of the analyte. During use, the hydrogel material is illuminated with illumination light in a first wavelength range while the hydrogel material interfaces with the dermal interstitial fluid layer of a subject, and a photosensor generates an output that corresponds to an amount of light received in a second wavelength range.


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