The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2020
Filed:
Mar. 17, 2011
Ikuro Maruyama, Kagoshima, JP;
Teruto Hashiguchi, Kagoshima, JP;
Salunya Tancharoen, Bangkok, TH;
Ko-ichi Kawahara, Kagoshima, JP;
Kenji Tanaka, Hyogo, JP;
Lyang-ja Lee, Hyogo, JP;
Ikuro Maruyama, Kagoshima, JP;
Teruto Hashiguchi, Kagoshima, JP;
Salunya Tancharoen, Bangkok, TH;
Ko-ichi Kawahara, Kagoshima, JP;
Kenji Tanaka, Hyogo, JP;
Lyang-ja Lee, Hyogo, JP;
KAGOSHIMA UNIVERSITY, Kagoshima, JP;
Abstract
The present invention provides an inhibitor of an autoimmune response to a periodontal bacterial enzymatic degradation product of keratin in gingival epithelium in a mammal having a periodontal bacterium in the oral cavity, containing a substance having affinity to the keratin or a degradation product thereof and/or a substance having affinity to an autoantibody to the degradation product, an agent for the prophylaxis and/or treatment of a periodontal disease and/or a complication thereof; a RANKL expression inhibitor containing a substance having affinity to the keratin or a degradation product thereof; and a method of diagnosing a periodontal disease including detecting the keratin or a degradation product thereof and/or an autoantibody thereto.