The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 2020

Filed:

Apr. 14, 2015
Applicant:

Sri International, Menlo Park, CA (US);

Inventor:

David E. Huber, Menlo Park, CA (US);

Assignee:

SRI International, Menlo Park, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/447 (2006.01); B01L 3/00 (2006.01); B01L 7/00 (2006.01); C12Q 1/686 (2018.01); C40B 60/12 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/686 (2013.01); B01L 3/502715 (2013.01); B01L 3/502723 (2013.01); B01L 3/502738 (2013.01); B01L 3/502746 (2013.01); B01L 7/52 (2013.01); G01N 27/4473 (2013.01); G01N 27/44791 (2013.01); B01L 2200/028 (2013.01); B01L 2200/0684 (2013.01); B01L 2200/10 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/087 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0819 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/168 (2013.01); B01L 2300/1822 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/082 (2013.01); C40B 60/12 (2013.01);
Abstract

Devices, systems and methods for the parallel detection of a set of distinct nucleic acid sequences use multiple sequence amplification and simultaneous hybridization readout. An automated nucleic acid analysis system comprises in microfluidic connection sample lysis, purification, PCR and detection modules configured to detect in parallel distinct nucleic acid sequences via multiple sequence amplification and simultaneous microarray hybridization readout. High performance microfluidic electroactive polymer (μEAP) actuators comprising a dead-end fluid chamber in which a surface of the chamber is an electrode covered with an EAP layer of dielectric elastomer are configured for particle sorting.


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