The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2020
Filed:
Mar. 27, 2013
Applicant:
Northeastern University, Boston, MA (US);
Inventors:
Assignee:
Northeastern University, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/00 (2006.01); C12Q 1/02 (2006.01); C12M 3/06 (2006.01); C12Q 1/18 (2006.01); G01N 33/543 (2006.01); G01N 33/58 (2006.01); B01L 3/00 (2006.01); C12M 1/34 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/025 (2013.01); B01L 3/502707 (2013.01); C12M 1/34 (2013.01); C12M 23/16 (2013.01); C12M 23/34 (2013.01); C12Q 1/18 (2013.01); G01N 33/54373 (2013.01); G01N 33/585 (2013.01); B01L 2200/0668 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/0896 (2013.01); B01L 2400/0472 (2013.01); Y10T 156/10 (2015.01);
Abstract
Nanofluidic devices and methods of the invention are capable of autonomously isolating individual microbial cells using constrictive channels and growing monocultures of the cells for automated characterization of their biochemical properties and interactions with mammalian cells. Single microbial cells, such as bacterial cells, are isolated directly from environmental sources and cultured using chemical factors from their native environment.