The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2020
Filed:
Jan. 09, 2017
Applicant:
Replimune Limited, Oxford, GB;
Inventor:
Robert Coffin, Oxford, GB;
Assignee:
Replimune Limited, Oxfordshire, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01); A61K 35/763 (2015.01); A61K 45/06 (2006.01); C07K 14/005 (2006.01); C07K 14/535 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); A61K 35/763 (2013.01); A61K 39/3955 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07K 14/005 (2013.01); C07K 14/535 (2013.01); C07K 16/2818 (2013.01); A61K 2039/505 (2013.01); C12N 2710/16621 (2013.01); C12N 2710/16622 (2013.01); C12N 2710/16632 (2013.01); C12N 2710/16633 (2013.01); C12N 2710/16643 (2013.01); C12N 2740/13022 (2013.01);
Abstract
The present invention provides a method of treating cancer, which comprises administering a therapeutically effective amount of an oncolytic virus, an inhibitor of the indoleamine 2,3-dioxygenase (IDO) pathway and a further antagonist of an immune co-inhibitory pathway or an agonist of an immune co-stimulatory pathway to a patient in need thereof.