The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2020
Filed:
Mar. 29, 2018
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Duke University, Durham, NC (US);
Barton Haynes, Durham, NC (US);
Garnett Kelsoe, Durham, NC (US);
Israel Lowy, Dobbs Ferry, NY (US);
Aris I. Baras, Mount Kisco, NY (US);
Lynn MacDonald, White Plains, NY (US);
John McWhirter, Tarrytown, NY (US);
Cagan Gurer, Valhalla, NY (US);
Karolina A. Meagher, Tarrytown, NY (US);
Andrew J. Murphy, Croton-on-Hudson, NY (US);
George D. Yancopoulos, Yorktown Heights, NY (US);
REGENERON PHARMACEUTICALS, INC., Tarrytown, NY (US);
DUKE UNIVERSITY, Durham, NC (US);
Abstract
Non-human animals with humanized immunoglobulin loci and methods of using them in vaccine design are described, as well as methods for making broadly neutralizing antibodies against infectious agents and pathogens are provided. Non-human animals with humanized immunoglobulin loci used in B-cell-lineage immunogen design in vaccine development are provided, as are methods of carrying out such design.