The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2020
Filed:
May. 09, 2019
Applicant:
Corning Incorporated, Corning, NY (US);
Inventors:
Na Li, Winchester, MA (US);
Jie Wang, Winchester, MA (US);
Christopher J. Patten, Scituate, MA (US);
Assignee:
Corning Incorporated, Corning, NY (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); C12N 5/00 (2006.01); C12N 5/02 (2006.01); C07K 14/705 (2006.01); C12N 15/85 (2006.01); A01N 1/02 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C07K 14/705 (2013.01); A01N 1/021 (2013.01); A01N 1/0284 (2013.01); C12N 5/00 (2013.01); C12N 5/067 (2013.01); C12N 5/069 (2013.01); C12N 15/85 (2013.01); G01N 33/5008 (2013.01); C12N 2510/00 (2013.01); G01N 2333/705 (2013.01);
Abstract
The present invention discloses cryopreserved recombinant cells for screening drug candidates that transiently overexpress one or more drug transporter proteins and/or drug metabolizing enzymes. Advantageously, such cells provide a cost-efficient consumable product that streamlines the process of screening whether drug candidates are substrates or inhibitors of drug transporter proteins and/or drug metabolizing enzymes.