logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10626095 B1

PDFFull Text
Date of Patent:
Apr. 21, 2020

Filed:

Jul. 16, 2014

Cyanotriazole compounds

Applicant:

Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;

Inventors:

Seiji Sato, Osaka, JP;

Satoshi Matsuda, Osaka, JP;

Chiharu Matsumura, Osaka, JP;

Motohiro Itotani, Osaka, JP;

Toshio Shinohara, Osaka, JP;

Shigekazu Fujita, Osaka, JP;

Yohji Sakurai, Osaka, JP;

Kuninori Tai, Osaka, JP;

Tae Fukushima, Osaka, JP;

Naohide Kanemoto, Osaka, JP;

Takashi Okamoto, Osaka, JP;

Assignee:

OTSUKA PHARMACEUTICAL CO., LTD., Tokyo, JP;

Attorney:

Sughrue Mion, PLLC

Primary Examiner:

Jeffrey S Lundgren

Assistant Examiner:

Michael J Schmitt

Int. Cl.
CPC ...
C07D 249/06 (2006.01); C07D 403/12 (2006.01); C07D 413/14 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 249/04 (2006.01); C07D 403/14 (2006.01); C07D 411/14 (2006.01); C07D 413/12 (2006.01); C07D 411/12 (2006.01); C07D 405/14 (2006.01); C07D 401/14 (2006.01); C07D 401/10 (2006.01); C07D 403/10 (2006.01); C07D 405/10 (2006.01); C07D 409/10 (2006.01); C07D 409/12 (2006.01); C07D 409/14 (2006.01); C07D 413/04 (2006.01); C07D 413/10 (2006.01); C07D 417/04 (2006.01); C07D 471/04 (2006.01); C07F 9/54 (2006.01);
U.S. Cl.
CPC ...
C07D 249/06 (2013.01); C07D 249/04 (2013.01); C07D 401/10 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/10 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/10 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/10 (2013.01); C07D 409/12 (2013.01); C07D 409/14 (2013.01); C07D 411/12 (2013.01); C07D 411/14 (2013.01); C07D 413/04 (2013.01); C07D 413/10 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07F 9/5456 (2013.01);
Abstract

This invention relates to a cyanotriazole compound represented by the formula (1): wherein each symbols are defined in the specification, or a salt thereof. The compound or a salt thereof stimulates the citric acid cycle activity and/or improves hyperglycemia with less side effects, and excellent safety, and therefore, it is useful for treating and/or preventing diseases or disorders on which citric acid cycle activation and/or improvement of hyperglycemia has a prophylactic and/or therapeutic effect, for example, diabetes, impaired glucose tolerance, insulin resistance, diabetic complications, obesity, dyslipidemia, hepatic steatosis, atherosclerosis and/or cardiovascular disease, as well as diseases or disorders that would benefit from stimulating energy expenditure.

Find Patent Forward Citations

Loading…