The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2020
Filed:
Jul. 11, 2016
Applicants:
Loyola University of Chicago, Chicago, IL (US);
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Daniel Paul Becker, Glenview, IL (US);
Cory Reidl, Franklin Grove, IL (US);
Maxwell Moore, Rockford, IL (US);
Tahirah K. Heath, Chicago, IL (US);
Walter Fast, Austin, TX (US);
Assignees:
LOYOLA UNIVERSITY OF CHICAGO, Chicago, IL (US);
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 45/06 (2006.01); C07D 209/08 (2006.01); A61P 31/04 (2006.01); C07D 249/04 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
C07D 209/08 (2013.01); A61K 45/06 (2013.01); A61P 31/04 (2018.01); C07D 249/04 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01);
Abstract
Indoline and tetrahydroquinoline sulfonyl compounds that can inhibit DapE and/or bacterial metallo-β-lactamases ('MBLs'), such as NDM-1 are disclosed. Also disclosed are methods of treating an individual suffering from a bacterial infection using the compounds disclosed herein.