The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 2020

Filed:

Nov. 20, 2015
Applicant:

Immunomet Therapeutics Inc., Houston, TX (US);

Inventors:

Hong Woo Kim, Daejeon, KR;

Jae Kap Jeong, Daejeon, KR;

Ji Sun Lee, Daejeon, KR;

Hye Jin Heo, Daejeon, KR;

Hong Bum Lee, Daejeon, KR;

Ji Ae Kook, Daejeon, KR;

Sung Wuk Kim, Gyeonggi-do, KR;

Assignee:

ImmunoMet Therapeutics Inc., Houston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 279/26 (2006.01); C07D 211/10 (2006.01); C07D 211/34 (2006.01); A61K 31/155 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07C 279/26 (2013.01); A61K 31/155 (2013.01); A61P 35/00 (2018.01); C07D 211/10 (2013.01); C07D 211/34 (2013.01);
Abstract

The present invention relates to a guanidine compound and a use thereof, and more specifically, to a guanidine derivative showing excellent effects of inhibiting cancer cell proliferation, cancer metastasis, and cancer recurrence; a preparation method thereof; and a pharmaceutical composition containing the same as an active ingredient. Compared to existing drugs, the guanidine derivative according to the present invention shows excellent effects of inhibiting cancer cell proliferation, cancer metastasis, and cancer recurrence even with small doses, and may thus be effectively used in preventing or treating various cancers such as uterine cancer, breast cancer, stomach cancer, brain cancer, rectal cancer, colorectal cancer, lung cancer, skin cancer, blood cancer, liver cancer, etc., inhibiting cancer cell proliferation and cancer metastasis.


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