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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10624974 B1

PDFFull Text
Date of Patent:
Apr. 21, 2020

Filed:

Oct. 15, 2015

Anti-ox40 antibody and application thereof

Applicant:

Dingfu Biotarget Co., Ltd., Suzhou, Jiangsu, CN;

Inventors:

Ting Xu, Jiangsu, CN;

Yan Luan, Jiangsu, CN;

Xiaoxiao Wang, Jiangsu, CN;

Jianjian Peng, Jiangsu, CN;

Shuli Ma, Jiangsu, CN;

Hui Ma, Jiangsu, CN;

Xiaolong Pan, Jiangsu, CN;

Shilong Fu, Jiangsu, CN;

Shanshan Ning, Jiangsu, CN;

Yeqiong Fei, Jiangsu, CN;

Meng Zhao, Jiangsu, CN;

Assignee:

Dingfu Biotarget Co., Ltd., Suzhou, Jiangsu, CN;

Attorneys:

Honigman LLP

Thomas A. Wootton, Esq.

Jonathan P. O'Brien

Primary Examiner:

Laura B Goddard

Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 47/68 (2017.01); C12N 15/63 (2006.01); A61P 35/00 (2006.01); C07H 21/04 (2006.01); C07K 16/30 (2006.01); C12N 5/07 (2010.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6851 (2017.08); A61K 39/3955 (2013.01); A61P 35/00 (2018.01); C07H 21/04 (2013.01); C07K 16/2878 (2013.01); C07K 16/30 (2013.01); C12N 5/06 (2013.01); C12N 15/63 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/75 (2013.01); C07K 2317/90 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

The present application provides an anti-OX40 human antibody. In particular, a human antibody specifically binding to OX40 is obtained with yeast display screening, and the affinity of the antibody is improved with affinity maturation. The present application also provides a use of the antibody for the prevention or treatment of tumors.

Find Patent Forward Citations

Xu, Ting. (2020). Anti-ox40 antibody and application thereof (U.S. Patent No. 10624974). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10624974

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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