The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2020
Filed:
Dec. 04, 2017
Deutsches Krebsforschungszentrum, Heidelberg, DE;
Ruprecht-karls-universität Heidelberg, Heidelberg, DE;
Barbara Leuchs, Heidelberg, DE;
Karsten Geletneky, Heidelberg, DE;
Jean Rommelaere, Heidelberg, DE;
Christiane Dinsart, Ladenburg, DE;
Michael Dahm, München, DE;
Ottheinz Krebs, München, DE;
DEUTSCHES KREBSFORSCHUNGSZENTRUM, Heidelberg, DE;
RUPRECHT-KARLS-UNIVERSITÄT HEIDELBERG, Heidelberg, DE;
Abstract
Described is a parvovirus formulation which comprises (a) at least 1×10pfu/ml of parvovirus H1 (H-1PV) or a related rodent parvovirus such as LuIII, Mouse minute virus (MMV), Mouse parvovirus (MPV), Rat minute virus (RMV), Rat parvovirus or Rat virus (RV) and (b) a pharmaceutically acceptable carrier containing 40-50% Iodixanol (w/v), 0.7-0.9 mmol CaCl×2 HO, 50-60 mmol NaCl, 0.9-1.2 mmol KCl, 0.7-0.95 mg/ml Tromethamine and 0.05-0.15 mg/ml Edetate calcium disodium. A preferred use is the therapy of a brain tumour by intratumoral injection.