The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 2020

Filed:

May. 11, 2015
Applicant:

Buddhist Tzu Chi Medical Foundation, Hualien, Hualien County, TW;

Inventors:

Dah-Ching Ding, Hualien, TW;

Kun-Chi Wu, Hualien, TW;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/28 (2015.01); A61K 31/728 (2006.01); C12N 5/077 (2010.01); C12N 5/0775 (2010.01); A61K 9/00 (2006.01); C12N 5/074 (2010.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61K 9/0019 (2013.01); A61K 31/728 (2013.01); C12N 5/0607 (2013.01); C12N 5/0667 (2013.01);
Abstract

The present invention provides a pharmaceutical composition comprising mesenchymal stem cells, a hyaluronan and a pharmaceutically acceptable carrier. The pharmaceutical composition is used for the treatment of the joint disease. The mesenchymal stem cells in the composition are at least one selected from the group consisting of infra-patellar fat pad stromal cells, bone marrow stem cells, Wharton's jelly stem cells and adipose derived stem cells. The concentration of the hyaluronan is in a range from 25% (v/v) to 75% (v/v). The present invention further provides a method for treating a joint disease, comprising a step of administrating a composition containing mesenchymal stem cells, a hyaluronan and a pharmaceutically acceptable carrier to an injured joint tissue of a subject.


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