The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2020
Filed:
Jun. 21, 2017
Applicant:
The Johns Hopkins University, Baltimore, MD (US);
Inventors:
Michela Gallagher, Baltimore, MD (US);
Ming Teng Koh, Baltimore, MD (US);
Assignee:
The Johns Hopkins University, Baltimore, MD (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4015 (2006.01); A61K 45/06 (2006.01); A61K 31/20 (2006.01); A61K 31/407 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); A61K 31/519 (2006.01); A61K 31/5513 (2006.01); A61K 31/554 (2006.01); A61P 25/00 (2006.01); A61P 25/18 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4015 (2013.01); A61K 31/20 (2013.01); A61K 31/407 (2013.01); A61K 31/454 (2013.01); A61K 31/496 (2013.01); A61K 31/519 (2013.01); A61K 31/554 (2013.01); A61K 31/5513 (2013.01); A61K 45/06 (2013.01); A61P 25/00 (2018.01); A61P 25/18 (2018.01);
Abstract
The invention relates to methods and compositions for treating schizophrenia or bipolar disorder (in particular, mania) by using a combination of a synaptic vesicle protein 2A (SV2A) inhibitor and an antipsychotic or their pharmaceutically acceptable salts, hydrates, solvates, polymorphs thereof. In some embodiments, the methods and the compositions are for treating one or more positive and/or negative symptoms, as well as cognitive impairment, associated with schizophrenia or bipolar disorder (in particular, mania).