The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2020
Filed:
Jan. 08, 2019
The University of Hong Kong, Hong Kong, CN;
Hongzhe Sun, Ap Lei Chau, HK;
Richard Yi Tsun Kao, Kowloon, HK;
Runming Wang, Hong Kong, HK;
Tsz Pui Lai, New Territories, HK;
Hongmin Zhang, Aberdeen, HK;
Hongyan Li, Ap Lei Chau, HK;
THE UNIVERSITY OF HONG KONG, Hong Kong, CN;
Abstract
The present disclosure relates to a pharmaceutical composition comprising: (a) β-lactam antibiotics and (b) a metallo-β-lactamases (MBLs) inhibitor. The inhibitor relates to Bi(III) compounds or the pharmaceutically acceptable salts thereof. The present patent also provides methods of making Bi(III) compounds or the pharmaceutically acceptable salts thereof. Also provided is a method for treating MBLs-producing bacterial infection using a metal replacement mechanism.