The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2020
Filed:
Jun. 02, 2011
Applicant:
Graham Peter Mead, Birmingham, GB;
Inventor:
Graham Peter Mead, Birmingham, GB;
Assignee:
The Binding Site Limited, Birmingham, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 27/447 (2006.01); C07K 16/06 (2006.01); C07K 16/42 (2006.01); G01N 33/561 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6857 (2013.01); C07K 16/065 (2013.01); C07K 16/42 (2013.01); G01N 27/44726 (2013.01); G01N 33/561 (2013.01);
Abstract
The invention provides a method detecting free light chains (FLCs) comprising: (i) providing a sample from a subject; (ii) mixing the sample with an anti-FLC specific antibody, or fragments thereof capable of specifically binding the FLC, to form a mixture; (iii) passing the mixture through a capillary tube by capillary zone electrophoresis (CZE); and (iv) detecting the presence of the antibody or fragment thereof after passage through at least a portion of the capillary tube. Capillary tubes for use in CZE and kits comprising capilliary tubes and at least one anti-FLC antibody are also provided.