The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2020

Filed:

Mar. 25, 2016
Applicants:

Vanderbilt University, Nashville, TN (US);

The Board of Regents of the University of Texas System, Austin, TX (US);

Inventors:

James E. Crowe, Jr., Nashville, TN (US);

Andrew I. Flyak, Nashville, TN (US);

Alexander Bukreyev, Galveston, TX (US);

Philipp Ilinykh, Galveston, TX (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/569 (2006.01); A61K 39/395 (2006.01); C07K 16/10 (2006.01); A61K 39/42 (2006.01); G01N 33/577 (2006.01); G01N 33/68 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56983 (2013.01); A61K 39/395 (2013.01); A61K 39/42 (2013.01); C07K 16/10 (2013.01); G01N 33/577 (2013.01); G01N 33/68 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); A61K 2039/545 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/55 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); G01N 2333/08 (2013.01);
Abstract

The present disclosure is directed to antibodies binding to and neutralizing ebolavirus and methods for use thereof. The present disclosure is directed to a method of detecting an ebolavirus infection in a subject comprising (a) contacting a sample from said subject with an antibody or antibody fragment having clone-paired heavy and light chain CDR sequences from Table 2, or an antibody fragment thereof; and (b) detecting ebolavirus glycoprotein in said sample by binding of said antibody or antibody fragment to antigen in said sample. In still further embodiments, the present disclosure concerns immunodetection kits for use with the immunodetection methods described above.


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