The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2020

Filed:

Nov. 16, 2015
Applicant:

GE Healthcare Bio-sciences Ab, Uppsala, SE;

Inventors:

Lena Nyholm, Uppsala, SE;

Lotta Hedkvist, Uppsala, SE;

Johan Arthursson, Uppsala, SE;

Eva Cecilia Olsson, Uppsala, SE;

Henrik Larsson, Uppsala, SE;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 30/86 (2006.01); B01D 15/24 (2006.01); G01N 30/82 (2006.01); B01D 15/10 (2006.01);
U.S. Cl.
CPC ...
G01N 30/8631 (2013.01); B01D 15/247 (2013.01); G01N 30/82 (2013.01); G01N 30/8644 (2013.01); B01D 15/10 (2013.01); B01D 15/24 (2013.01);
Abstract

The present invention relates to a method for performing liquid chromatography purification of one or more target molecules from a sample comprising: providing an eluent flow having one or more target molecules, measuring an output parameter indicative of the content of the one or more target molecules in the eluent flow, storing output parameter data, and dividing the eluent flow into consecutive eluent fractions, dividing the output parameter data into corresponding data fractions, in each data fraction obtaining a value indicative of characteristic behavior of the measured output parameter, identifying trends in the measured output parameter based upon the obtained value in consecutive data fractions, and identifying peak(s) in the measured output parameter correlated to eluent fractions based upon the identified trends, whereby information of identified peak(s) and correlated eluent fraction(s) can be presented and purified sample(s) from the eluent may be collected.


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