The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2020
Filed:
Aug. 31, 2017
Applicant:
Agilent Technologies, Inc., Santa Clara, CA (US);
Inventors:
Jordy J. Hsiao, Santa Clara, CA (US);
Hongfeng Yin, Cupertino, CA (US);
Oscar G. Potter, Santa Clara, CA (US);
Assignee:
AGILENT TECHNOLOGIES, INC., Santa Clara, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 30/00 (2006.01); G01N 30/72 (2006.01); G01N 30/16 (2006.01); G01N 30/88 (2006.01); G01N 30/06 (2006.01); B01D 15/30 (2006.01); B01D 15/32 (2006.01); B01D 15/34 (2006.01); B01D 15/42 (2006.01); G01N 30/34 (2006.01); G01N 30/02 (2006.01);
U.S. Cl.
CPC ...
G01N 30/7233 (2013.01); B01D 15/305 (2013.01); B01D 15/325 (2013.01); B01D 15/34 (2013.01); B01D 15/424 (2013.01); G01N 30/06 (2013.01); G01N 30/16 (2013.01); G01N 30/34 (2013.01); G01N 30/88 (2013.01); G01N 2030/027 (2013.01); G01N 2030/065 (2013.01); G01N 2030/884 (2013.01); G01N 2030/8831 (2013.01);
Abstract
The present disclosure generally relates to improved methods for separating and analyzing compounds by liquid chromatography, particularly when coupled with mass spectrometry. The methods include the addition of an additive to a mobile phase carrying a sample. The mobile phase additive may be effective for improving peak shapes of targeted analytes in acquired data, and/or eliminating or at least reducing ion suppression. The methods are particularly suited for anionic compounds such as phosphorylated compounds.