The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2020
Filed:
Mar. 30, 2017
Applicant:
Industry-academic Cooperation Foundation, Yonsei University, Seoul, KR;
Inventors:
Assignee:
INDUSTRY-ACADEMIC COOPERATION FOUNDATION, Yonsei University, Seoul, unknown;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6806 (2018.01); C12N 15/63 (2006.01); C12N 9/22 (2006.01); C12Q 1/6832 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6806 (2013.01); C12N 9/22 (2013.01); C12N 15/63 (2013.01); C12Q 1/6832 (2013.01);
Abstract
Cloning vectors encoding endonuclease capable of removing false positives. Attempts to diagnose and/or select appropriate treatment methods via genetic screening can be rendered inaccurate do the presence of false positive. The error causing false positives may include double-stranded nucleic acids comprising a bulge and/or Y-junction. Expression vectors encoding an endonuclease capable of removing such error causing false positives are disclosed, along with methods of utilizing the encoded endonucleases to increase diagnostic accuracy and permit selection of more appropriate treatments.