The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2020

Filed:

Jun. 26, 2017
Applicant:

Contipro A.s., Dolni Dobrouc, CZ;

Inventors:

Radovan Buffa, Humenne, SK;

Tomas Bobula, Svit, SK;

Petra Sedova, Ceska Trebova, CZ;

Ivana Basarabova, Medzilaborce, SK;

Pavlina Prochazkova, Vlkos, CZ;

Hana Vagnerova, Dolni Cermna, CZ;

Iva Doleckova, Hradec Kralove, CZ;

Sona Moravcikova, Jamne nad Orlici, CZ;

Vladimir Velebny, Zamberk, CZ;

Assignee:

Contipro a.s., Dolni Dobrouc, CZ;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08B 37/08 (2006.01); C08B 37/00 (2006.01); A61K 31/728 (2006.01); A61K 31/731 (2006.01); A61K 31/737 (2006.01); A61K 31/726 (2006.01);
U.S. Cl.
CPC ...
C08B 37/0072 (2013.01); A61K 31/726 (2013.01); A61K 31/728 (2013.01); A61K 31/731 (2013.01); A61K 31/737 (2013.01); C08B 37/00 (2013.01); C08B 37/0042 (2013.01); C08B 37/0069 (2013.01);
Abstract

The invention relates to the preparation of new polysaccharide derivatives comprising a double bond in the positions 4 and 5 of the pyranose cycle. The method of preparation consists in the oxidation of OH group in the position 6 to an aldehyde, followed by the elimination to form a double —C═C— bond in the positions 4 and 5, and the final reduction of the aldehyde group in the position 6 into the original alcohol. The derivatives of polysaccharides prepared according to the invention show an enhanced antioxidant activity and some of them also a selective negative influence on carcinoma cell viability. (formula) where R represents —NH—CO—CHor —OH.


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