The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2020

Filed:

Jan. 08, 2016
Applicant:

Sigea S.r.l., Trieste, IT;

Inventors:

Luca Stucchi, Frazione Tissano, IT;

Rita Gianni, Monrupino, IT;

Alessandra Sechi, Trieste, IT;

Assignee:

BMG PHARMA S.P.A., Milan, IT;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C08B 37/08 (2006.01); C08L 5/08 (2006.01); A61K 31/728 (2006.01); A61K 8/73 (2006.01); A61Q 19/08 (2006.01); A61K 9/00 (2006.01); A61Q 19/00 (2006.01); A61L 31/04 (2006.01); A61L 27/20 (2006.01);
U.S. Cl.
CPC ...
C08B 37/0072 (2013.01); A61K 8/735 (2013.01); A61K 9/0014 (2013.01); A61K 31/728 (2013.01); A61L 27/20 (2013.01); A61L 31/042 (2013.01); A61Q 19/00 (2013.01); A61Q 19/08 (2013.01); C08L 5/08 (2013.01); A61L 2430/34 (2013.01);
Abstract

The present invention relates to a process for the preparation of hyaluronic acid butyrate, or a salt thereof, acceptable for pharmaceutical or cosmetic use or as a medical device, comprising reacting hyaluronic acid, salified with sodium or another alkali metal, in aqueous solution with butyryl-imidazolide in the presence of sodium carbonate. The present invention also relates to pharmaceutical formulations, cosmetic formulations or medical devices containing the hyaluronic acid sodium salt (HA) butyric esters produced by said process.


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