The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2020
Filed:
Feb. 17, 2017
Applicant:
The Governing Council of the University of Toronto, Toronto, CA;
Inventors:
Wei Zhang, Mississauga, CA;
Sachdev Sidhu, Toronto, CA;
Assignee:
Other;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); C07H 21/04 (2006.01); C12N 9/10 (2006.01); C12N 9/00 (2006.01); G01N 30/02 (2006.01); G01N 30/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/47 (2013.01); C07H 21/04 (2013.01); C12N 9/10 (2013.01); C12N 9/104 (2013.01); C12N 9/93 (2013.01); C12Y 603/02019 (2013.01); G01N 30/02 (2013.01); G01N 30/00 (2013.01); G01N 2030/022 (2013.01); G01N 2030/027 (2013.01);
Abstract
The invention provides ubiquitin variants that specifically bind to HECT E3 ligases, and methods of using these variants to modulate the activity of HECT E3 ligases.