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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10618909 B1

PDFFull Text
Date of Patent:
Apr. 14, 2020

Filed:

Apr. 25, 2019

Bicyclic derivatives, a process for their preparation and pharmaceutical compositions containing them

Applicants:

Les Laboratoires Servier, Suresnes, FR;

Vernalis (R&d) Ltd, Winnersh, GB;

Inventors:

Balázs Bálint, Fót, HU;

Márton Csékei, Dunakeszi, HU;

Zoltán Szabó, Budapest, HU;

Zoltán Szlávik, Budapest, HU;

András Kotschy, Törökbálint, HU;

Maïa Chanrion, Issy les Moulineaux, FR;

Olivier Geneste, Rueil-Malmaison, FR;

I-Jen Chen, Cambridge, GB;

James Edward Paul Davidson, Great Shelford, GB;

James Brooke Murray, Linton, GB;

Szabolcs Sipos, Budapest, HU;

Levente Ondi, Veresegyház, HU;

Ágnes Proszenyák, Budapest, HU;

Assignees:

LES LABORATOIRES SERVIER, Suresnes, FR;

VERNALIS (R&D) LTD, Winnersh Berkshire, GB;

Attorney:

Hueschen and Sage

Primary Examiner:

Charanjit Aulakh

Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 495/04 (2006.01); C07D 403/12 (2006.01); C07D 333/56 (2006.01); C07D 405/04 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 491/04 (2006.01); C07D 209/12 (2006.01); C07D 307/80 (2006.01); C07D 307/81 (2006.01); A61P 35/02 (2006.01); C07D 491/048 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61P 35/02 (2018.01); C07D 209/12 (2013.01); C07D 307/80 (2013.01); C07D 307/81 (2013.01); C07D 333/56 (2013.01); C07D 403/12 (2013.01); C07D 405/04 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 491/04 (2013.01); C07D 491/048 (2013.01); A61K 45/06 (2013.01); A61K 2300/00 (2013.01);
Abstract

Compounds of formula (I): wherein R, R, R, R, R, R, R, R, R, W, A and n are as defined in the description. Medicinal products containing the same which are useful in treating conditions requiring a pro-apoptotic agent.

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