The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2020
Filed:
Jun. 23, 2016
Bristol-myers Squibb Company, Princeton, NJ (US);
John V. Duncia, Newtown, PA (US);
Daniel S. Gardner, Furlong, PA (US);
John Hynes, Washington Crossing, PA (US);
John E. Macor, Washington Crossing, PA (US);
Natesan Murugesan, Princeton Junction, NJ (US);
Joseph B. Santella, Springfield, PA (US);
Hong Wu, New Hope, PA (US);
Durgarao Kantheti, Bangalore, IN;
Satheesh Kesavan Nair, Bangalore, IN;
Venkatram Reddy Paidi, Bangalore, IN;
Sreekantha Ratna Kumar, Bangalore, IN;
Kandhasamy Sarkunam, Hosur, IN;
Ramesh Kumar Sistla, Bangalore, IN;
Subba Rao Polimera, Bangalore, IN;
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
Disclosed are compounds of Formula (I) Formula (I) or salts thereof, wherein HET is a heteroaryl selected from oxazolyl, pyrazolyl, imidazo[1,2-b]pyridazin-3-yl, and pyrazolo[1,5-a]pyrimidin-3-yl, wherein said heteroaryl is attached to the pyridinyl group in the compound of Formula (I) by a carbon ring atom in the heteroaryl and wherein said heteroaryl is substituted with zero to 2 R; and R, R, and Rare define herein. Also disclosed are methods of using such compounds as modulators of IRAK4, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing inflammatory and autoimmune diseases, or in the treatment of cancer.