The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2020
Filed:
Apr. 15, 2016
Applicant:
Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;
Inventors:
Hong Liu, Shanghai, CN;
Yu Zhou, Shanghai, CN;
Dong Zhang, Shanghai, CN;
Jian Li, Shanghai, CN;
Hualiang Jiang, Shanghai, CN;
Kaixian Chen, Shanghai, CN;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 401/12 (2006.01); C07D 239/26 (2006.01); C07D 417/06 (2006.01); C07D 417/10 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 277/30 (2006.01); C07D 213/56 (2006.01); C07D 213/75 (2006.01); C07D 213/82 (2006.01); C07D 401/10 (2006.01); C07D 277/32 (2006.01); C07D 231/56 (2006.01); C07D 261/08 (2006.01); C07D 263/32 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 413/10 (2006.01); C07D 413/12 (2006.01); C07D 491/10 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 213/56 (2013.01); C07D 213/75 (2013.01); C07D 213/82 (2013.01); C07D 231/56 (2013.01); C07D 239/26 (2013.01); C07D 261/08 (2013.01); C07D 263/32 (2013.01); C07D 277/30 (2013.01); C07D 277/32 (2013.01); C07D 401/06 (2013.01); C07D 401/10 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 413/10 (2013.01); C07D 413/12 (2013.01); C07D 417/06 (2013.01); C07D 417/10 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 491/10 (2013.01);
Abstract
Compounds of formula I are provided. Also provided are methods of preparing the compounds of formula (I), and methods of using the compounds of formula (I) as a negative allosteric modulator of a metabotropic glutamate receptor (mGluR) subtype 5.