The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2020
Filed:
Mar. 30, 2017
Children's Medical Center Corporation, Boston, MA (US);
Denisa D. Wagner, Dover, MA (US);
Tobias A. Fuchs, Gunzenbach, DE;
Simon De Meyer, Zwevegem, BE;
Kimberly Martinod, Boston, MA (US);
Alexander Brill, Birmingham, GB;
Grace M. Thomas, Marseilles, FR;
CHILDREN'S MEDICAL CENTER CORPORATION, Boston, MA (US);
Abstract
Embodiments of the technology described herein are based upon the discoveries that neturophil extracellular traps (NETs) provide a stimulus for thrombus formation and that NETs are present in stored blood products. Accordingly, some embodiments are directed towards methods of treating stored blood products to prevent transfusion-related injuries e.g., preventing transfusion-related acute lung injury (TRALI), by treating blood transfusion products with an anti-Neutrophil Extracellular Trap (NET) compound.