The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2020
Filed:
Dec. 23, 2015
Beijing University of Agriculture, Beijing, CN;
Can Liu, Beijing, CN;
Lanqing Ma, Beijing, CN;
Dequan Dou, Beijing, CN;
Yuanxia Sun, Beijing, CN;
Long Rong, Beijing, CN;
Xiaomeng Zhao, Beijing, CN;
Juntao Li, Beijing, CN;
Yan Wang, Beijing, CN;
Zhengzi Bi, Beijing, CN;
Xiaozhu Bi, Beijing, CN;
Haiwen Hu, Beijing, CN;
BEIJING UNIVERSITY OF AGRICULTURE, Beijing, CN;
Abstract
The present invention relates to a chemical and pharmaceutical technology, and in particular to a STAT3 and ERK signal pathway inhibitor and a use thereof. The present invention provides a STAT3 and ERK signal pathway inhibitor. The inhibitor mainly consists of a mogroside and/or an analog thereof. The mogroside and the analog thereof inhibit the phosphorylation of a transcription factor STAT3 and the phosphorylation of an ERK. The method for preparing the mogroside and the analog has the characteristics of simpleness, strong operability and high purity of products. The present invention further provides a use of the STAT3 and ERK signal pathway inhibitor in the preparation of drugs for treating tumors, which realizes the purposes of inhibiting the proliferation of cancer cells and promoting the apoptosis of cancer cells and has a very good inhibition effect on cancers.