The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2020
Filed:
Oct. 24, 2014
Applicants:
Ospedale San Raffaele S.r.l., Milan, IT;
Fondazione Telethon, Rome, IT;
Inventors:
Luigi Naldini, Milan, IT;
Bernhard Rudolf Gentner, Milan, IT;
Erika Zonari, Milan, IT;
Francesco Boccalatte, Milan, IT;
Assignees:
OSPEDALE SAN RAFFAELE S.R.L., Milan, IT;
FONDAZIONE TELETHON, Rome, IT;
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/28 (2015.01); C12N 5/0789 (2010.01); C12N 15/86 (2006.01); A61K 48/00 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61K 48/0091 (2013.01); C12N 5/0647 (2013.01); C12N 15/86 (2013.01); C12N 7/00 (2013.01); C12N 2510/00 (2013.01); C12N 2740/15043 (2013.01);
Abstract
A method of preparing a therapeutic cell population for clinical use from a starting population of cells comprising haematopoietic stem cells, said method comprising separating a population of cells that substantially do not express CD38 but which express CD34 from the starting population of cells, and transducing the separated cell population with a vector to obtain the therapeutic cell population.