The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2020

Filed:

Oct. 17, 2017
Applicant:

Miltenyi Biotec Gmbh, Bergisch Gladbach, DE;

Inventors:

Dominik Eckardt, Bergisch Gladbach, DE;

Andreas Bosio, Cologne, DE;

Olaf Hardt, Köln, DE;

Andrzej Dzionek, Overath, DE;

Stefan Tomiuk, Köln, DE;

Jutta Kollet, Bonn, DE;

Assignee:

Miltenyi Biotech, GmbH, Bergisch Gladbach, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 65/00 (2009.01); A61K 48/00 (2006.01); A61K 35/17 (2015.01); A61K 39/00 (2006.01); A61K 47/65 (2017.01); A61P 35/00 (2006.01); C07K 14/725 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 39/0011 (2013.01); A61K 47/65 (2017.08); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C07K 14/70596 (2013.01);
Abstract

The present invention is directed to ligand like a chimeric antigen receptor (CAR), comprising an antigen binding domain specific for one or more antigens selected from the group consisting of CLA, CD142, CD73, CD49c, CD66c, CD104, CD318 and TSPAN8; cell populations expressing such CARs and the use of the cell populations for cancer therapy.


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