The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2020
Filed:
Jun. 10, 2016
Medibeacon Inc., St. Louis, MO (US);
Raghavan Rajagopalan, Solon, OH (US);
Richard B. Dorshow, St. Louis, MO (US);
William L. Neumann, St. Louis, MO (US);
Dennis A. Moore, St. Louis, MO (US);
MediBeacon Inc., St. Louis, MO (US);
Abstract
The present invention relates to pyrazine derivatives such as those represented by Formulas I and II. Xto Xof Formulas I and II may be characterized as electron withdrawing groups, while Yto Yof Formulas I and II may be characterized as electron donating groups. Pyrazine derivatives of the present invention may be utilized in assessing organ (e.g., kidney) function. In a particular example, an effective amount of a pyrazine derivative that is capable of being renally cleared may be administered into a patient's body. The pyrazine derivative may capable of one or both absorbing and emanating spectral energy of at least about 400 nm (e.g., visible and/or infrared light). At least some of the derivative that is in the body may be exposed to spectral energy and, in turn, spectral energy may emanate from the derivative. This emanating spectral energy may be detected and utilized to determine renal function of the patient.