The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2020
Filed:
Sep. 29, 2015
Applicant:
Pfizer Inc., New York, NY (US);
Inventors:
Puja Sapra, River Edge, NJ (US);
Boris Shor, Cliffside Park, NJ (US);
Assignee:
Pfizer Inc., New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/40 (2006.01); A61K 31/166 (2006.01); A61K 31/4025 (2006.01); A61K 31/4015 (2006.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01); A61K 31/337 (2006.01);
U.S. Cl.
CPC ...
A61K 31/40 (2013.01); A61K 31/166 (2013.01); A61K 31/4015 (2013.01); A61K 31/4025 (2013.01); A61K 45/06 (2013.01); A61K 47/6855 (2017.08); A61K 47/6857 (2017.08); A61P 35/00 (2018.01); A61K 31/337 (2013.01); A61K 2300/00 (2013.01);
Abstract
This invention relates to combinations of an auristatin or an auristatin-based antibody-drug-conjugate (ADC) with second active agents including PI3K/mTOR inhibitors, MEK inhibitors, taxanes, or other anti-cancer agents, and methods of treating abnormal cell growth by administering these combinations to patients.