The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2020
Filed:
Sep. 12, 2018
The Usa, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Sri International, Menlo Park, CA (US);
Irving W. Wainer, Washington, DC (US);
Michel Bernier, Pikesville, MD (US);
Lawrence Robert Toll, Redwood City, CA (US);
Lucita Arenas Jimenez, Menlo Park, CA (US);
The USA, as represented by the Secretary, Department of Health and Human Services, Bethesda, MD (US);
SRI International, Menlo Park, CA (US);
Abstract
This disclosure concerns the discovery of the use of fenoterol and (R,R)- and (R,S)-fenoterol analogues for the treatment of a tumor expressing a β2-adrenergic receptor, such as a primary brain tumor, including a glioblastoma or astrocytoma expressing a β2-adrenergic receptor. In one example, the method includes administering to a subject a therapeutically effective amount of fenoterol, a specific fenoterol analogue or a combination thereof to reduce one or more symptoms associated with the tumor, thereby treating the tumor in the subject.