The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2020

Filed:

Mar. 29, 2019
Applicant:

Lynthera Corporation, Lancaster, PA (US);

Inventors:

Arthur Jing-Min Yang, York, PA (US);

Roman C. Domszy, Lancaster, PA (US);

Jeffry Chung-Hwang Yang, York, PA (US);

Assignee:

Lynthera Corporation, Lancaster, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/54 (2006.01); A61F 9/00 (2006.01); G02C 7/04 (2006.01); A61K 9/00 (2006.01); A61M 31/00 (2006.01);
U.S. Cl.
CPC ...
A61F 9/0017 (2013.01); A61K 9/0051 (2013.01); A61L 27/54 (2013.01); G02C 7/04 (2013.01); A61L 2300/624 (2013.01); A61L 2300/626 (2013.01); A61L 2430/16 (2013.01); A61M 31/002 (2013.01);
Abstract

The present invention relates to a nanocomposite ocular device that can release drugs within a close distance to the ocular surface and provide controlled and sustained release of the drug at a constant rate. The device can achieve both optical and medical functions. The device comprises a drug, one or more reservoir domains, and a barrier layer configured to block the drug diffusion paths from the reservoir domain to the ocular surface in the eye of the subject, wherein the drug partitions between the reservoir domain and the barrier layer, and the equilibrium drug solubility in the reservoir domain is at least five folds higher than that in the barrier layer.


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