The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2020
Filed:
Jan. 04, 2017
Case Western Reserve University, Cleveland, OH (US);
Pallavi Tiwari, Shaker Heights, OH (US);
Anant Madabhushi, Shaker Heights, OH (US);
Gavin Hanson, Cleveland Heights, OH (US);
Jhimli Mitra, Cleveland, OH (US);
Case Western Reserve University, Cleveland, OH (US);
Abstract
Methods and apparatus quantify mass effect deformation in diagnostic images of patients demonstrating glioblastoma multiforme (GBM). One example apparatus includes an image acquisition circuit that acquires an image of a region of tissue demonstrating GBM pathology, a delineation circuit that segments a tumor region from the image, a pre-processing circuit that generates a pre-processed image by pre-processing the segmented image, a registration circuit that registers the pre-processed image with a template image of a healthy brain, a deformation quantification circuit that computes a set of differences between a position of a brain sub-structure represented in the registered image relative to the position of the brain sub-structure represented in the template image. Embodiments may include a classification circuit that classifies the region of tissue as a long or short-term survivor based, at least in part, on the set of differences.