The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2020

Filed:

Nov. 16, 2015
Applicant:

Fraunhofer-gesellschaft Zur Forderung Der Angewandten Forschung E.v., Munich, DE;

Inventors:

Anke Burger-Kentischer, Stuttgart, DE;

Steffen Rupp, Stuttgart, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/92 (2006.01); G01N 33/558 (2006.01); G01N 33/569 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
G01N 33/92 (2013.01); G01N 33/54386 (2013.01); G01N 33/558 (2013.01); G01N 33/56916 (2013.01); G01N 2400/50 (2013.01); G01N 2469/10 (2013.01); G01N 2800/26 (2013.01); G01N 2800/709 (2013.01);
Abstract

The invention relates to a competitive immunoassay test system as well as a method to simply and rapidly detect pyrogens contained in a sample by means of the pyrogen binding domain of pattern recognition receptors. The test system comprises an assay carrier having at least one immobilized pyrogen binding domain of a pattern recognition receptor with a labeled, displaceable ligand, wherein the displacement of the ligand is indicated by a pyrogen contained in the sample by a color reaction of the labeling. The assay carrier preferably also has at least one immobilized ligand capture protein, which binds the displaced ligand and thereby initiates a color reaction of the labeling.


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