The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2020

Filed:

May. 21, 2015
Applicant:

Zafena Ab, Borensberg, SE;

Inventor:

Mats Ranby, Vreta Kloster, SE;

Assignee:

ZAFENA AB, Borensberg, SE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/86 (2006.01); C12Q 1/56 (2006.01);
U.S. Cl.
CPC ...
G01N 33/86 (2013.01); C12Q 1/56 (2013.01);
Abstract

An assay to determine anticoagulants in a blood or blood plasma sample, wherein the assay comprises analyses with at least two wet chemistry prothrombine time (PT) methods. The assay comprises measuring PT in a first reaction mixture with a first PT method and measuring PT in a second reaction mixture with a second PT method, wherein the concentration of blood or blood plasma in the second reaction mixture differs from the concentration of blood or blood plasma in the first reaction mixture. The PT methods are calibrated to give the same or approximately the same PT results for reference samples which lack anticoagulants of interest for the assay. Further, calculating a difference in PT from the measurements, wherein if the difference in PT is 1) significant, this is indicative of a presence of anticoagulants in the sample, or 2) non-significant, this is indicative of an absence of anti-coagulants above detectable level in the sample.


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