The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2020

Filed:

Jun. 08, 2016
Applicant:

Institut Pasteur, Paris, FR;

Inventors:

Muhamed-Kheir Taha, Saint Maur des Fosses, FR;

Alain Agnememel, Freneuse, FR;

Assignee:

INSTITUT PASTEUR, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/569 (2006.01); C07K 16/12 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56911 (2013.01); C07K 16/1217 (2013.01); C07K 2317/14 (2013.01); C07K 2317/33 (2013.01); C07K 2317/565 (2013.01); G01N 2333/22 (2013.01); G01N 2400/10 (2013.01); G01N 2469/10 (2013.01); G01N 2800/26 (2013.01);
Abstract

The present invention is directed to monoclonal antibodies and antigen-binding portions thereof, specific for the capsular polysaccharides ofserogroup X (NmX), wherein said antibodies or portions thereof are characterized by the sequences of the 6 CDR of the variable regions of the heavy and light chains. These antibodies are suitable for in vitro detection ofserogroup X especially in a biological sample without purification of the capsular polysaccharides. The invention also concerns said monoclonal antibodiesor adequate portions thereofin different diagnostic tests and methods, in order to detect NmX. The invention discloses also a rapid diagnostic test for detecting NmX in a biological fluid.


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