The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2020
Filed:
Nov. 30, 2016
Applicant:
Liposcience, Inc., Raleigh, NC (US);
Inventors:
James D. Otvos, Apex, NC (US);
Elias J. Jeyarajah, Raleigh, NC (US);
Justyna E. Wolak-Dinsmore, Durham, NC (US);
Thomas M. O'Connell, Chapel Hill, NC (US);
Dennis W. Bennett, Shorewood, WI (US);
Steven P. Matyus, Durham, NC (US);
Stanley L. Hazen, Pepper Pike, OH (US);
Assignee:
Liposcience, Inc., Morrisville, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); G01N 33/50 (2006.01); G01N 24/08 (2006.01); G01R 33/465 (2006.01); G01N 33/66 (2006.01); G16B 5/00 (2019.01); G16B 45/00 (2019.01);
U.S. Cl.
CPC ...
G01N 24/08 (2013.01); G01N 24/088 (2013.01); G01N 33/66 (2013.01); G01R 33/465 (2013.01); G16B 5/00 (2019.02); G16B 45/00 (2019.02); G01N 2800/323 (2013.01);
Abstract
A defined peak region residing between about 3.2 and 3.4 ppm of a proton NMR spectrum of an in vitro biosample is electronically evaluated to determine a level of trimethylamine-N-oxide ('TMAO'). The biosamples may be any suitable biosamples including human serum with a normal biologic range of between about 1-50 μM or urine with a normal biologic range of between about 0-1000 μM.