The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2020
Filed:
Dec. 04, 2014
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Steven P. Treon, Jamaica Plain, MA (US);
Lian Xu, Waltham, MA (US);
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Abstract
Diagnostic assays for discriminating Waldenstrom's Macroglobulinemia from IgM monoclonal gammopathy of undetermined significance are provided. The method comprises obtaining a biological sample from a subject in need thereof, performing an allele-specific polymerase chain reaction assay to determine in the biological sample a level of a transcript comprising a mutation at position 38182641 in chromosome 3p22.2, and providing a report indicating whether delta Cvalue of the biological sample is less than a reference value, wherein the subject has Waldenstrom's Macroglobulinemia if the delta Cvalue is less than the reference value.