The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2020
Filed:
Dec. 12, 2018
Applicant:
Pacific Biosciences of California, Inc., Menlo Park, CA (US);
Inventors:
Andrei Fedorov, San Bruno, CA (US);
John Lyle, Fremont, CA (US);
Keith Bjornson, Fremont, CA (US);
Jeremiah Hanes, Woodside, CA (US);
Assignee:
Pacific Biosciences of California, Inc., Menlo Park, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6869 (2018.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); C12Q 1/6869 (2013.01); C12Q 2527/125 (2013.01); C12Q 2563/137 (2013.01);
Abstract
Compositions, kits, methods and systems for single molecule nucleotide sequencing comprising producing polymerase reactions having monovalent cations that control the median pulse width for incorporated nucleotides are disclosed. The levels of monovalent cations are used to control pulse width while allowing other sequencing parameters to remain within a desirable range.