The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2020
Filed:
Feb. 13, 2018
Applicant:
Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing, CN;
Inventors:
Yuling Liu, Beijing, CN;
Cuiping Zhou, Beijing, CN;
Zhihui Song, Beijing, CN;
Lin Li, Beijing, CN;
Hongliang Wang, Beijing, CN;
Xuejun Xia, Beijing, CN;
Renyun Wang, Beijing, CN;
Wujun Dong, Beijing, CN;
Dujia Jin, Beijing, CN;
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 17/02 (2006.01); A61K 9/107 (2006.01); A61K 9/14 (2006.01); A61K 47/24 (2006.01); C07K 14/62 (2006.01); A61K 38/00 (2006.01); A61K 9/127 (2006.01);
U.S. Cl.
CPC ...
C07K 17/02 (2013.01); A61K 9/1075 (2013.01); A61K 9/127 (2013.01); A61K 9/145 (2013.01); A61K 47/24 (2013.01); C07K 14/62 (2013.01); A61K 38/00 (2013.01);
Abstract
Provided are an insulin-lipid complex, a preparation method thereof, and a formulation thereof. The insulin-lipid complex is prepared by compounding insulin and a lipid material in an organic solvent system containing a low boiling point acid, and drying. The mass ratio of insulin to the lipid material is 1:3˜1:20. An oil solution of the insulin-lipid complex and vesicles containing insulin are further provided.