The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2020

Filed:

Jul. 21, 2016
Applicant:

Zhucheng Haotian Pharm Co., Ltd, Zhucheng, Weifang, Shandong, CN;

Inventors:

Liping Zhu, Shandong, CN;

Xuefeng Mei, Shanghai, CN;

Ying Huang, Shanghai, CN;

Jianrong Wang, Shanghai, CN;

Qi Zhang, Shanghai, CN;

Assignee:

ZHUCHENG HAOTIAN PHARM CO., LTD, Zhucheng, Weifang, Shandong, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 15/24 (2006.01); A23L 2/60 (2006.01); A23L 33/00 (2016.01); A61K 47/26 (2006.01); C07H 15/26 (2006.01); A23L 27/30 (2016.01); C07H 1/06 (2006.01); A23L 2/02 (2006.01); A61K 47/38 (2006.01); A61K 31/4402 (2006.01); A23L 19/00 (2016.01); C07H 1/08 (2006.01);
U.S. Cl.
CPC ...
C07H 15/24 (2013.01); A23L 2/02 (2013.01); A23L 2/60 (2013.01); A23L 19/00 (2016.08); A23L 27/30 (2016.08); A23L 33/00 (2016.08); A61K 31/4402 (2013.01); A61K 47/26 (2013.01); A61K 47/38 (2013.01); C07H 1/06 (2013.01); C07H 1/08 (2013.01); C07H 15/26 (2013.01); A23L 27/33 (2016.08); C07B 2200/13 (2013.01);
Abstract

Provided are crystalline form A of rebaudioside D, and a preparation method and application therefor. In X-ray powder diffraction analysis measured using Cu-Kα rays and with 2θ being expressed in degrees, crystalline form A of rebaudioside D has significant characteristic diffraction peaks at least at 4.53, 6.38, 12.76, 13.52, 17.48, 17.96, 20.07 and 22.63. The preparation method is a suspension method, a solvent evaporation method or a cooling method. The preparation method has a simple process, and is convenient to operate. A rebaudioside D crystalline form A product has a good degree of crystallinity, good water solubility, and high chemical stability.


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