The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2020
Filed:
Jan. 13, 2017
Bristol-myers Squibb Company, Princeton, NJ (US);
Leon M. Smith, II, Somerset, NJ (US);
Vladimir Ladziata, Ewing, NJ (US);
Indawati De Lucca, Pennington, NJ (US);
Donald J. P. Pinto, Churchville, PA (US);
Michael J. Orwat, New Hope, PA (US);
Andrew K. Dilger, Ewing, NJ (US);
Kumar Balashanmuga Pabbisetty, Piscataway, NJ (US);
Wu Yang, Princeton Junction, NJ (US);
Scott A. Shaw, Lawrence Township, NJ (US);
Peter W. Glunz, Yardley, PA (US);
Manoranjan Panda, Bangalore, IN;
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically-acceptable salts thereof wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.